| Date: | 24–30 January 2022 |
| Edition: | 12th |
| Surface: | Hard / Indoor |
| Location: | Andrézieux-Bouthéon, France |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Ana Bogdan |
| Champd: |  Estelle Cascino / Jessika Ponchet |
| Main Name: | Open Andrézieux-Bouthéon 42 |
The 2022 Engie Open Andrézieux-Bouthéon 42 was a professional tennis tournament played on indoor hard courts. It was the twelfth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Andrézieux-Bouthéon, France between 24 and 30 January 2022.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| France | Clara Burel | 77 | 1 | |
| France | Océane Dodin | 85 | 2 | |
| Romania | Ana Bogdan | 116 | 3 | |
| Anna-Lena Friedsam | 138 | 4 | ||
| Stefanie Vögele | 145 | 5 | ||
 Russian Federation | Anna Blinkova | 153 | 6 | |
 United Kingdom | Katie Boulter | 155 | 7 | |
 Spain | Rebeka Masarova | 157 | 8 |
The following players received wildcards into the singles main draw:
Émeline Dartron Salma Djoubri Evita Ramirez Margaux RouvroyThe following players received entry from the qualifying draw:
Erika Andreeva Manon Arcangioli Clarisse Aussert
Berfu Cengiz Léolia Jeanjean Victoria Muntean
Raluca ȘerbanSee main article: 2022 Engie Open Andrézieux-Bouthéon 42 – Singles.
Ana Bogdan def. Anna Blinkova, 7–5, 6–3See main article: 2022 Engie Open Andrézieux-Bouthéon 42 – Doubles.
Estelle Cascino / Jessika Ponchet def. Alicia Barnett / Olivia Nicholls, 6–4, 6–1