| Date: | 10–16 October 2022 |
| Edition: | 10th |
| Surface: | Hard / Indoor |
| Location: | Trnava, Slovakia |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: | Eva Lys |
| Champd: | Sofya Lansere /  Rebecca Šramková |
| Main Name: | Empire Women's Indoor |
| Before Year: | 2020 |
The 2022 Empire Women's Indoor 2 was a professional tennis tournament played on indoor hard courts. It was the tenth edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Trnava, Slovakia between 10 and 16 October 2022.[1]
See main article: 2022 Empire Women's Indoor 2 – Singles.
Anna Karolína Schmiedlová, 6–2, 4–6, 6–2See main article: 2022 Empire Women's Indoor 2 – Doubles.
Rebecca Šramková def. Lee Pei-chi / Wu Fang-hsien, 4–6, 6–2, [11–9]| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Czech Republic | Linda Nosková | 97 | 1 | |
| Slovakia | Anna Karolína Schmiedlová | 107 | 2 | |
 Ukraine | Daria Snigur | 115 | 3 | |
| Vitalia Diatchenko | 116 | 4 | ||
 United Kingdom | ||||
 France | Léolia Jeanjean | 133 | 6 | |
 United States | Caty McNally | 151 | 7 | |
| Eva Lys | 168 | 8 |
The following players received wildcards into the singles main draw:
Nikola Daubnerová Lucie Havlíčková Ela PláteníkováThe following player received entry into the singles main draw using a junior exempt:
The following players received entry from the qualifying draw:
Timea Jarušková Linda Klimovičová Aneta Laboutková
Lola Radivojević Rebecca ŠramkováThe following players received entry as Lucky Losers: