| Year: | 2022 |
| Team: | Duquesne Dukes |
| Sport: | football |
| Conference: | Northeast Conference |
| Short Conf: | NEC |
| Record: | 4–7 |
| Conf Record: | 3–4 |
| Head Coach: | Jerry Schmitt |
| Hc Year: | 18th |
| Off Coach: | Anthony Doria |
| Oc Year: | 7th |
| Codef Coach1: | Mike Craig |
| Codc1 Year: | 1st |
| Codef Coach2: | Scott Farison |
| Codc2 Year: | 1st |
| Stadium: | Arthur J. Rooney Athletic Field |
The 2022 Duquesne Dukes football team represented Duquesne University as a member of the Northeast Conference (NEC) during the 2022 NCAA Division I FCS football season. The Dukes, led by 18th-year head coach Jerry Schmitt, played their home games at Arthur J. Rooney Athletic Field.
See also: 2022 Florida State Seminoles football team.
See also: 2022 Youngstown State Penguins football team.
See also: 2022 Hawaii Rainbow Warriors football team.
See also: 2022 Stonehill Skyhawks football team.
See also: 2022 Merrimack Warriors football team.
See also: 2022 Central Connecticut Blue Devils football team.
See also: 2022 LIU Sharks football team.
See also: 2022 Sacred Heart Pioneers football team.
See also: 2022 Saint Francis Red Flash football team.
See also: 2022 Wagner Seahawks football team.