| Date: | 31 October–6 November 2022 |
| Edition: | 28th |
| Surface: | Hard (Indoor) |
| Location: | Midland, Michigan, United States |
| Venue: | Greater Midland Tennis Center |
| Category: | WTA 125 |
| Prize Money: | $115,000 |
| Champs: |  Caty McNally |
| Champd: | Asia Muhammad / Alycia Parks |
The 2022 Dow Tennis Classic was a professional tennis tournament played on indoor hard courts. It was the twenty-eighth edition of the tournament which was also part of the 2022 WTA 125 tournaments. It took place at the Greater Midland Tennis Center in Midland, Michigan, United States between 31 October and 6 November 2022.[1]
See main article: 2022 Dow Tennis Classic – Singles.
Caty McNally def. Anna-Lena Friedsam, 6–3, 6–2.See main article: 2022 Dow Tennis Classic – Doubles.
Asia Muhammad / Alycia Parks def. Anna-Lena Friedsam / 
Nadiia Kichenok, 6–2, 6–3| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 China | Zhang Shuai | 24 | 1 | |
| United States | Madison Brengle | 51 | 2 | |
| China | Zhu Lin | 62 | 3 | |
| China | ||||
 Colombia | Camila Osorio | 86 | 5 | |
| Varvara Gracheva | 94 | 6 | ||
| United States | Caty McNally | 108 | 7 | |
 Japan | Moyuka Uchijima | 109 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Fernanda Contreras Gómez → replaced by Sachia Vickery
Carol Zhao Marta Kostyuk → replaced by Robin Anderson
Rebecca Peterson → replaced by Anna-Lena Friedsam Lesia Tsurenko → replaced by Asia Muhammad Louisa Chirico Katie Volynets → replaced by Ashlyn Krueger Yuan Yue → replaced by Sophie Chang| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| United States | Asia Muhammad | United States | Alycia Parks | 105 | 1 | |
| United States | Sophie Chang | United States | Angela Kulikov | 118 | 2 | |
| United States | Kaitlyn Christian | Lidziya Marozava | 129 | 3 | ||
| United States | Catherine Harrison | United States | Sabrina Santamaria | 167 | 4 |
The following pair received a wildcard into the doubles main draw:
Karolína Beránková / Elizabeth Coleman