See main article: 2022 Delray Beach Open.
Ariel Behar and Gonzalo Escobar were the defending champions[1] but chose to play in Rio de Janeiro instead.
Marcelo Arévalo and Jean-Julien Rojer won the title, defeating Aleksandr Nedovyesov and Aisam-ul-Haq Qureshi in the final, 6–2, 6–7(5–7), [10–4].