| Competition: | 44th Chicago Marathon |
| Location: | Chicago, Illinois, U.S. |
| Men: | Benson Kipruto |
| Men Win Value: | 2:04:24 |
| Women: | Ruth Chepngetich |
| Women Win Value: | 2:14:18 |
| Wheelchair Men: | Marcel Hug |
| Wheelchair Men Win Value: | 1:25:20 |
| Wheelchair Women: | Susannah Scaroni |
| Wheelchair Women Win Value: | 1:45:48 |
| Previous: | 2021 |
| Next: | 2023 |
The 2022 Chicago Marathon was the 44th edition of the annual marathon race in Chicago, held on Sunday, . An Elite Platinum Label marathon, it was the third of four World Marathon Majors events to be held over the span of six weeks. More than 40,000 runners were expected to take part in the event.
Seifu Tura of Ethiopia, the winner of the previous year's race, was expected to return to defend his title. His compatriot Herpasa Negasa, who ran a marathon with a time of 2:03:40 in Dubai in 2019, was expected to join him. Also expected to make an appearance were Kenyan runners Bernard Koech and Elisha Rotich.
Kenyan runner Ruth Chepng'etich, the defending champion, was the favorite to win the women's race. Also scheduled to join the field were Ethiopian runners Ruti Aga and Haven Hailu Desse, and Kenyan runners Celestine Chepchirchir and Vivian Kiplagat.
U.S. wheelchair athlete Tatyana McFadden, who had previously won the Chicago Marathon nine times, was also expected to defend her title.
Results for the top ten in the running races and top three in the wheelchair races are listed below.
| Position | Athlete | Nationality | Time | |
|---|---|---|---|---|
| 2:04:24 | ||||
| 2:04:49 | ||||
| 2:05:01 | ||||
| 4 | 2:07:15 | |||
| 5 | 2:07:53 | |||
| 6 | 2:08:05 | |||
| 7 | 2:08:16 | |||
| 8 | 2:08:22 | |||
| 9 | 2:08:26 | |||
| 10 | 2:08:53 |
| Position | Athlete | Nationality | Time | |
|---|---|---|---|---|
| 2:14:18 | ||||
| 2:18:29 | ||||
| 2:20:52 | ||||
| 4 | 2:21:41 | |||
| 5 | 2:23:41 | |||
| 6 | 2:25:14 | |||
| 7 | 2:26:23 | |||
| 8 | 2:28:07 | |||
| 9 | 2:29:37 | |||
| 10 | 2:30:28 |
| Position | Athlete | Nationality | Time | |
|---|---|---|---|---|
| 1:25:20 | ||||
| 1:33:11 | ||||
| 1:33:13 |
| Position | Athlete | Nationality | Time | |
|---|---|---|---|---|
| 1:45:48 | ||||
| 1:49:46 | ||||
| 1:49:52 |