| Date: | November 14 – 20 |
| Edition: | 15th |
| Category: | ATP Challenger Tour |
| Surface: | Hard (indoor) |
| Location: | Drummondville, Canada |
| Champs: |  Vasek Pospisil |
| Champd: |  Julian Cash / Henry Patten |
| Main Name: | Challenger de Drummondville |
| Before Year: | 2020 |
The 2022 Challenger Banque Nationale de Drummondville was a professional tennis tournament played on indoor hard courts. It was the 15th edition of the tournament and part of the 2022 ATP Challenger Tour. It took place in Drummondville, Canada between November 14 and 20, 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Ecuador | Emilio Gómez | 107 | 1 | |
 United States | Michael Mmoh | 115 | 2 | |
| Canada | Vasek Pospisil | 118 | 3 | |
 Argentina | Juan Pablo Ficovich | 140 | 4 | |
 France | ||||
| France | Antoine Escoffier | 216 | 6 | |
| Canada | Alexis Galarneau | 222 | 7 | |
| Canada | Gabriel Diallo | 248 | 8 |
The following players received wildcards into the singles main draw:
Taha Baadi Justin Boulais Marko StakusicThe following player received entry into the singles main draw using a protected ranking:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Liam Draxl
Maks Kaśnikowski Joshua Lapadat Roy SmithThe following player received entry as a lucky loser:
See main article: 2022 Challenger Banque Nationale de Drummondville – Singles.
Vasek Pospisil def. Michael Mmoh 7–6(7–5), 4–6, 6–4.See main article: 2022 Challenger Banque Nationale de Drummondville – Doubles.
Julian Cash / Henry Patten def. Arthur Fery / Giles Hussey 6–3, 6–3.
