| Year: | 2022 |
| Team: | Cal Poly Mustangs |
| Sport: | football |
| Conference: | Big Sky Conference |
| Short Conf: | Big Sky |
| Record: | 2–9 |
| Conf Record: | 1–7 |
| Head Coach: | Beau Baldwin |
| Hc Year: | 3rd |
| Codef Coach1: | Will Plemons |
| Codc1 Year: | 1st |
| Codef Coach2: | Cody Von Appen |
| Codc2 Year: | 1st |
| Stadium: | Alex G. Spanos Stadium |
The 2022 Cal Poly Mustangs football team represented California Polytechnic State University as a member of the Big Sky Conference the 2022 NCAA Division I FCS football season. The Mustangs were led by third-year head coach Beau Baldwin and now played their home games at Mustang Memorial Field in San Luis Obispo, California.
On July 25, 2022, during the virtual Big Sky Kickoff, the Mustangs were predicted to finish tenth in the Big Sky by both the coaches and media.[1]
| 1 | Montana | 111 (3) | |
| 2 | Sacramento State | 110 (4) | |
| 3 | Montana State | 109 (5) | |
| 4 | Weber State | 84 | |
| 5 | UC Davis | 82 | |
| 6 | Eastern Washington | 76 | |
| 7 | Northern Arizona | 62 | |
| 8 | Idaho | 45 | |
| 9 | Portland State | 42 | |
| 10 | Cal Poly | 33 | |
| T-11 | Idaho State | 19 | |
| T-11 | Northern Colorado | 19 |
| 1 | Montana | 356 (14) | |
| 2 | Montana State | 352 (13) | |
| 3 | Sacramento State | 335 (4) | |
| 4 | Weber State | 261 | |
| 5 | UC Davis | 255 (1) | |
| 6 | Eastern Washington | 236 | |
| 7 | Northern Arizona | 191 | |
| 8 | Portland State | 146 | |
| 9 | Idaho | 142 | |
| 10 | Cal Poly | 85 | |
| 11 | Northern Colorado | 71 | |
| 12 | Idaho State | 66 |
The Mustangs did not have any players selected to the preseason all-Big Sky team.[2]
See also: 2022 Fresno State Bulldogs football team.
See also: 2022 San Diego Toreros football team.
See also: 2022 South Dakota Coyotes football team.
See also: 2022 Sacramento State Hornets football team.
See also: 2022 Northern Arizona Lumberjacks football team.
See also: 2022 Idaho State Bengals football team.
See also: 2022 Eastern Washington Eagles football team.
See also: 2022 UC Davis Aggies football team and Battle for the Golden Horseshoe.
See also: 2022 Montana Grizzlies football team.
See also: 2022 Montana State Bobcats football team.
See also: 2022 Portland State Vikings football team.