The 2022 Braga Open was a professional tennis tournament played on clay courts. It was the fourth edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Braga, Portugal between 19 and 25 September 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Nuno Borges | 93 | 1 | ||
 Spain | Carlos Taberner | 121 | 2 | |
 Italy | Franco Agamenone | 147 | 3 | |
 France | Alexandre Müller | 148 | 4 | |
| France | Manuel Guinard | 149 | 5 | |
 Czech Republic | Vít Kopřiva | 151 | 6 | |
| Alexander Shevchenko | 166 | 7 | ||
| France | Benoît Paire | 176 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
Javier Barranco Cosano Ugo Blanchet Pablo Llamas Ruiz Imanol López Morillo
Nicolas Moreno de AlboranThe following player received entry as a lucky loser:
Nicolas Moreno de Alboran def. 
Matheus Pucinelli de Almeida 6–2, 6–4.See main article: 2022 Braga Open – Doubles.
Vít Kopřiva / Jaroslav Pospíšil def. 
Jeevan Nedunchezhiyan / Christopher Rungkat 3–6, 6–3, [10–4].