| Date: | 31 October–6 November 2022 |
| Edition: | 1st |
| Surface: | Hard / Outdoor |
| Location: | Barranquilla, Colombia |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Panna Udvardy |
| Champd: | Tímea Babos /  Kateryna Volodko |
The 2022 Barranquilla Open is a professional tennis tournament played on outdoor hard courts. It is the first edition of the tournament which is part of the 2022 ITF Women's World Tennis Tour. It takes place in Barranquilla, Colombia between 31 October and 6 November 2022.[1]
See main article: 2022 Barranquilla Open – Singles.
Panna Udvardy def. 
Laura Pigossi, 6–2, 7–5See main article: 2022 Barranquilla Open – Doubles.
Tímea Babos / Kateryna Volodko def. Carolina Alves / Valeriya Strakhova, 3–6, 7–5, [10–7]| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Hungary | Panna Udvardy | 80 | 1 | |
| Brazil | Laura Pigossi | 103 | 2 | |
| Hungary | Réka Luca Jani | 110 | 3 | |
| Despina Papamichail | 148 | 4 | ||
 Argentina | María Lourdes Carlé | 172 | 5 | |
| Brazil | Carolina Alves | 182 | 6 | |
 France | Carole Monnet | 218 | 7 | |
| Eva Vedder | 243 | 8 | ||
 China | You Xiaodi | 271 | 9 | |
| Argentina | Julia Riera | 277 | 10 | |
| Lena Papadakis | 285 | 11 | ||
| Brazil | Gabriela Cé | 286 | 12 | |
| Hungary | Tímea Babos | 304 | 13 | |
 Mexico | Ana Sofía Sánchez | 323 | 14 | |
 United States | Hurricane Tyra Black | 343 | 15 | |
| Ukraine | Kateryna Volodko | 351 | 16 |
The following players received wildcards into the singles main draw:
Yuliana Monroy Laura Pigossi Gabriella Price María Camila Torres Murcia Kelly Loana Vargas GonzálezThe following players received entry from the qualifying draw:
Madison Bourguignon Ana Candiotto Lya Fernández Rebeca Pereira Lauren Proctor Kaitlin QuevedoThe following player received entry as a lucky loser:
Ana María Becerra