| Date: | 28 February–6 March 2022 |
| Edition: | 1st |
| Surface: | Hard / Outdoor |
| Location: | Arcadia, California, United States |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: |  Rebecca Marino |
| Champd: |  Ashlyn Krueger / Robin Montgomery |
The 2022 Arcadia Women's Pro Open was a professional tennis tournament played on outdoor hard courts. It was the first edition of the tournament which was part of the 2022 ITF Women's World Tennis Tour. It took place in Arcadia, California, United States between 28 February and 6 March 2022.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 France | Chloé Paquet | 118 | 1 | |
 Australia | Maddison Inglis | 123 | 2 | |
 United Kingdom | Harriet Dart | 124 | 3 | |
 Serbia | Aleksandra Krunić | 125 | 4 | |
| Canada | Rebecca Marino | 153 | 5 | |
| United States | Katie Volynets | 155 | 6 | |
| United States | Robin Anderson | 168 | 7 | |
| Arianne Hartono | 171 | 8 |
The following players received wildcards into the singles main draw:
Katie Codd Liv Hovde Elvina Kalieva Raveena KingsleyThe following players received entry using protected rankings:
The following player received entry using a junior exempt:
The following players received entry from the qualifying draw:
Reese Brantmeier Kayla Day Ellie Douglas Quinn Gleason Ashlyn Krueger Maegan Manasse Robin Montgomery
Ena ShibaharaSee main article: 2022 Arcadia Women's Pro Open – Singles.
Rebecca Marino def. Alycia Parks, 7–6(7–0), 6–1See main article: 2022 Arcadia Women's Pro Open – Doubles.
Ashlyn Krueger / Robin Montgomery def. Harriet Dart / 
Giuliana Olmos, walkover