See main article: 2022 Abierto Mexicano Telcel.
Feliciano López and Stefanos Tsitsipas defeated Marcelo Arévalo and Jean-Julien Rojer in the final, 7–5, 6–4 to win the doubles title at the 2022 Mexican Open.
Ken and Neal Skupski were the defending champions,[1] but chose to play in Dubai instead.