| Club: | Anderlecht |
| Season: | 2022–23 |
| Chairman: | Wouter Vandenhaute |
| Manager: | Brian Riemer |
| Stadium: | Constant Vanden Stock Stadium |
| League: | Pro League |
| League Result: | 11th |
| Cup1: | Belgian Cup |
| Cup1 Result: | Seventh round |
| Cup2: | UEFA Europa Conference League |
| Cup2 Result: | Quarter-finals |
| League Topscorer: | Islam Slimani (8) |
| Season Topscorer: | Fábio Silva (11) |
| Prevseason: | 2021–22 |
| Nextseason: | 2023–24 |
The 2022–23 season was the 115th season in the history of R.S.C. Anderlecht and their 87th consecutive season in the top flight. The club participated in the Belgian Pro League, the Belgian Cup, and the UEFA Europa Conference League.
| scope=col | Player | Transferred from | scope=col; style="width: 91px;" | Fee | scope=col | Date | scope=col | Source | ||
|---|---|---|---|---|---|---|---|---|---|---|
| 32 | LDU Quito | €1,900,000 | [2] | |||||||
| 24 |  IFK Norrköping | €3,000,000 | ||||||||
| 21 |  Roma | €1,890,000 | ||||||||
| 14 | Benfica | Free | [3] | |||||||
| 33 | FC Midtjylland | €4,200,000 | ||||||||
| 13 |  Brest | Free |
See main article: 2022–23 Belgian Pro League.
The league fixtures were announced on 22 June 2022.[4]
See main article: 2022–23 Belgian Cup.
See main article: 2022–23 UEFA Europa Conference League.
The draw for the third qualifying round was held on 18 July 2022.
The draw for the play-off round was held on 2 August 2022.
See main article: 2022–23 UEFA Europa Conference League group stage.
The draw for the group stage was held on 26 August 2022.[5]
See main article: 2022–23 UEFA Europa Conference League knockout phase.
The knockout round play-offs draw was held on 7 November 2022.
The knockout round play-offs draw was held on 24 February 2023.
|-! colspan=14 style=background:#dcdcdc; text-align:center| Goalkeepers|-! colspan=14 style=background:#dcdcdc; text-align:center| Defenders |-! colspan=14 style=background:#dcdcdc; text-align:center| Midfielders|-! colspan=14 style=background:#dcdcdc; text-align:center| Forwards |-! colspan=14 style=background:#dcdcdc; text-align:center| Players transferred out during the season