The 2022–23 Denmark Series is the 58th season of the Denmark Series, the fifth tier of the Danish football league structure organised by the Danish FA (DBU). The season marked a transitional phase in the structure of the Danish leagues.
This season, the league was divided into four groups of ten teams each. After the regular season (18 rounds), the top two teams in the four groups are promoted to the promotin group, for three spot in the 2023–24 Danish 3rd Division, the relegation for this season is based on which three team is relegated from the 2022–23 Danish 3rd Division depending on the teams are from east or west of the Great Belt.
The top two teams in the four groups are promoted for a spot in the Promotion round where the four top team, Vejgaard BK, Marienlyst, Holbæk B&I and Avarta, carry over 3 points. There play for three spots in the 2023–24 Danish 3rd Division
Eight teams are relegated from the 2023-24 season to the tier 6 level.