2022–2023 mpox outbreak in the United Kingdom explained

Image Upright:1.5
Disease:Mpox
Location:United Kingdom
First Case:London
Arrival Date:6 May 2022(ago)
Confirmed Cases:3,279 (and 134 highly probable cases)
Deaths:0
Website:UK Government

The 2022–2023 mpox outbreak in the United Kingdom is part of the larger outbreak of human mpox caused by the West African clade (type) of the monkeypox virus. The United Kingdom was the first country, outside of the endemic African areas, to experience an outbreak., there were 2,208 confirmed cases in the United Kingdom, with 2,115 in England, 54 in Scotland, 24 in Wales, and 15 in Northern Ireland.[1]

Background

An ongoing outbreak of mpox was confirmed on 6 May 2022, beginning with a British resident who, after travelling to Nigeria (where the disease is endemic), presented symptoms consistent with mpox on 29 April 2022. The resident returned to the United Kingdom on 4 May, creating the country's index case of the outbreak.[2] The origin of several of the cases of mpox in the United Kingdom is unknown. Some monitors saw community transmission taking place in the London area as of mid-May,[3] but it has been suggested that cases were already spreading in Europe in the previous months.[4]

Transmission

A large portion of those infected were believed to have not recently traveled to areas of Africa where mpox is normally found, such as Nigeria, the Democratic Republic of the Congo as well as central and western Africa. It is believed to be transmitted by close contact with sick people, with extra caution for those individuals with lesions on their skin or genitals, along with their bedding and clothing. The CDC has also stated that individuals should avoid contact and consumption of dead animals such as rats, squirrels, monkeys and apes along with wild game or lotions derived from animals in Africa.[5]

In addition to more common symptoms, such as fever, headache, swollen lymph nodes, and rashes or lesions, some patients have also experienced proctitis, an inflammation of the rectum lining. CDC has also warned clinicians to not rule out mpox in patients with sexually transmitted infections since there have been reports of co-infections with syphilis, gonorrhea, chlamydia, and herpes.[6]

History

The first known case was detected in the beginning of May 2022, in a British resident who had travelled to Lagos and Delta State in Nigeria, in areas where mpox is considered to be an endemic disease. The person developed a rash on 29 April while in Nigeria and flew back to the United Kingdom, arriving on 4 May,[7] and presented to hospital later the same day. Mpox infection was immediately suspected, and the patient was hospitalised at Guy's Hospital and isolated, then tested positive for the virus on 6 May.

In late May, cases started to be reported in the other constituent countries, with Public Health Scotland reporting its first case on 23 May.[8] [9] Public Health Wales and the Public Health Agency of Northern Ireland each reported one case on 26 May.[10] [11]

On 1 June, a case was reported in Gibraltar, a British Overseas Territory.[12]

On 30 August 2022, 3413 cumulative cases (3,279 confirmed and 134 highly probable cases) of human mpox up to (and including) 29 August were reported for the UK.[13]

UK cumulative and weekly cases

Responses

On 22 May, Education Secretary Nadhim Zahawi said "we're taking it very, very seriously" and that the UK government had already started purchasing smallpox vaccines.[14]

The UK Health Security Agency (UKHSA) advised people who have had close contact with a person infected with mpox to self-isolate for 21 days. Self-isolation is not mandatory.[15]

Furthermore, to combat the continued spread of the outbreak, the UKHSA has offered doses of the Imvanex smallpox vaccine, also effective against mpox, to people having had close contact with people confirmed to having been infected.

On 30 May, the four main public health agencies published a consensus statement describing the principles they will put in use, with the aim of limiting community transmission.[16]

Number of cases confirmed in constituent countries

Cases of mpox!Constituent country!Case(s)
15
54
24
2,115
Total2,208

See also

Notes and References

  1. Web site: Monkeypox outbreak: epidemiological overview . 2022-07-08 . GOV.UK . en.
  2. Web site: 16 May 2022 . Monkeypox – United Kingdom of Great Britain and Northern Ireland . live . https://web.archive.org/web/20220517223855/https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON381 . 17 May 2022 . 17 May 2022 . World Health Organization.
  3. Web site: Pinkstone . Joe . 17 May 2022 . Monkeypox 'spreading in sexual networks' . live . https://web.archive.org/web/20220517223851/https://www.telegraph.co.uk/news/2022/05/17/monkeypox-likely-sexually-transmissible-infection-health-officials/ . 17 May 2022 . 17 May 2022 . The Telegraph.
  4. Web site: Nsofor . Ifeanyi . 2 June 2022 . Opinion: Media coverage of monkeypox paints it as an African virus. That makes me mad . 2 June 2022 . NPR.
  5. Web site: Vargas . Ramon Antonio . 2022-06-07 . US raises monkeypox alert level but says risk to public remains low . 2022-06-09 . the Guardian . en.
  6. Web site: Monkeypox update: Where the outbreak stands now .
  7. News: 14 May 2022 . Monkeypox contact tracing extended to Scotland . BBC News . live . 17 May 2022 . https://web.archive.org/web/20220517232614/https://www.bbc.co.uk/news/uk-scotland-61435476 . 17 May 2022.
  8. Web site: Monkeypox cases confirmed in England – latest updates . . 2 June 2022.
  9. Web site: First case of monkeypox confirmed in Scotland. live. 23 May 2022. 24 May 2022. https://web.archive.org/web/20220524192333/https://publichealthscotland.scot/news/2022/may/first-case-of-monkeypox-confirmed-in-scotland/.
  10. Web site: Monkeypox spread continues with first case reported in Wales . . 26 May 2022 . 26 May 2022.
  11. News: Monkeypox: First case identified in NI . BBC News . 26 May 2022 . 26 May 2022.
  12. Web site: GHA confirms first case of monkeypox in Gibraltar . . 1 June 2022. en.
  13. Web site: Monkeypox outbreak: epidemiological overview, 30 August 2022.
  14. Web site: UK Confirms Local Transmission of Monkeypox . . 22 May 2022 . 24 May 2022 . https://web.archive.org/web/20220524192725/https://ewn.co.za/2022/05/22/uk-confirms-local-transmission-of-monkeypox . live .
  15. Web site: Taylor . Chloe . 2022-05-23 . People coming into contact with monkeypox are now being advised to quarantine for 3 weeks . 2022-05-24 . Fortune . en.
  16. Web site: Principles for monkeypox control in the UK: 4 nations consensus statement .