| Year: | 2021 |
| Team: | Washington Huskies |
| Sport: | football |
| Conference: | Pac-12 Conference |
| Division: | North Division |
| Short Conf: | Pac-12 |
| Record: | 4–8 |
| Conf Record: | 3–6 |
| Head Coach: | Jimmy Lake |
| Hc Year: | 2nd |
| Hc Games: | first 9 games |
| Head Coach2: | Bob Gregory |
| Hc Games2: | interim; final 3 games |
| Off Coach: | John Donovan |
| Oc Year: | 2nd |
| Off Scheme: | Multiple |
| Def Coach: | Bob Gregory |
| Dc Year: | 1st |
| Codef Coach1: | Ikaika Malloe |
| Codc1 Year: | 2nd |
| Def Scheme: | 4–2–5 |
| Stadium: | Alaska Airlines Field at Husky Stadium |
The 2021 Washington Huskies football team represented the University of Washington during the 2021 NCAA Division I FBS football season. The Huskies were led by second year head coach Jimmy Lake for the first ten games. The team announced a new head coach, Kalen DeBoer, on November 30. The Huskies played their home games at Husky Stadium in Seattle, Washington, and competed in the North Division of the Pac-12 Conference.
See also: 2021 Montana Grizzlies football team.
Entering the season ranked 20th in the nation, UW struggled immensely in their opener against FCS opponent Montana en route to a shocking 13–7 defeat at the hands of the Grizzlies. Despite entering as 23.5-point favorites over the Griz, the Huskies' offense was shut out for the final 55 minutes of the game, as starting quarterback Dylan Morris tossed 3 picks and zero touchdowns. The Huskies only had 291 yards of total offense. The upset marked only the second time in 20 meetings all-time between the schools that Montana had ever beaten Washington and was also Montana's first win in the series in over 100 years, dating back to 1920. In addition to being the first time that UW has lost to an FCS opponent, it was also only the fifth instance of an FCS team beating an Top-25 FBS team.
See also: 2021 Michigan Wolverines football team.
See also: 2021 Arkansas State Red Wolves football team.
See also: 2021 California Golden Bears football team.
See also: 2021 Oregon State Beavers football team.
See also: 2021 UCLA Bruins football team.
See also: 2021 Arizona Wildcats football team.
See also: 2021 Stanford Cardinal football team.
See also: 2021 Oregon Ducks football team.
See also: 2021 Arizona State Sun Devils football team.
See also: 2021 Colorado Buffaloes football team.
See also: 2021 Washington State Cougars football team and Apple Cup.
| Team | Poll | Pre | Wk 2 | Wk 3 | Wk 4 | Wk 5 | Wk 6 | Wk 7 | Wk 8 | Wk 9 | Wk 10 | Wk 11 | Wk 12 | Wk 13 | Wk 14 | Final |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Washington | AP | 20 | NR | NR | NR | NR | NR | NR | ||||||||
| C | 21 | NR | NR | NR | NR | NR | NR | NR | ||||||||
| CFP | Not released | |||||||||||||||
| Improvement in ranking | ||
| Drop in ranking | ||
| Not ranked previous week | ||
| No change in ranking from previous week | ||
| RV | Received votes but were not ranked in Top 25 of poll | |
| Head coach (fired mid season) | Eastern Washington (1999) | ||
| Wide receivers coach (became offensive coordinator mid season) | Montana State (2004) | ||
| Running backs coach /special teams coordinator | Hawai'i (2003) | ||
| Assistant defensive backs coach | Stanford (2013) | ||
| Tight ends coach | Dartmouth (2010) | ||
| John Donovan | Offensive coordinator/quarterbacks coach (fired mid season) | Johns Hopkins (1996) | |
| Defensive coordinator/inside linebackers coach | Washington State (1987) | ||
| Defensive backs coach | USC (2009) | ||
| Offensive line coach | Boise State (2002) | ||
| Co-defensive coordinator/outside linebackers coach | Washington (1997) | ||
| Defensive line coach | Austin Peay State (2014) | ||
| Head strength and conditioning coach | Minnesota (1999) | ||
| Chief of staff | Miami (OH) (1999) |