| Year: | 2021 |
| Sport: | football |
| Team: | Villanova Wildcats |
| Conference: | Colonial Athletic Association |
| Short Conf: | CAA |
| Statsrank: | 8 |
| Fcscoachrank: | 8 |
| Record: | 10–3 |
| Conf Record: | 7–1 |
| Head Coach: | Mark Ferrante |
| Hc Year: | 5th |
| Off Coach: | Chris Boden |
| Oc Year: | 3rd |
| Def Coach: | Ola Adams |
| Dc Year: | 3rd |
| Stadium: | Villanova Stadium |
| Champion: | CAA co-champion |
| Bowl: | NCAA Division I Quarterfinal |
| Bowl Result: | L 21–35 vs. South Dakota State |
The 2021 Villanova Wildcats football team represented Villanova University in the 2021 NCAA Division I FCS football season. They were led by fifth-year head coach Mark Ferrante and played their home games at Villanova Stadium. They competed as a member of the Colonial Athletic Association.
See also: 2021 Penn State Nittany Lions football team.