| Year: | 2021 |
| Team: | VMI Keydets |
| Sport: | football |
| Conference: | Southern Conference |
| Short Conf: | SoCon |
| Record: | 6–5 |
| Conf Record: | 4–4 |
| Head Coach: | Scott Wachenheim |
| Hc Year: | 7th |
| Off Coach: | Billy Cosh |
| Oc Year: | 2nd |
| Def Coach: | Tom Clark |
| Dc Year: | 7th |
| Stadium: | Alumni Memorial Field |
The 2021 VMI Keydets football team represented the Virginia Military Institute in the 2021 NCAA Division I FCS football season as a member of the Southern Conference (SoCon). The Keydets were led by seventh-year head coach Scott Wachenheim and played their home games at Alumni Memorial Field in Lexington, Virginia.