| Year: | 2021 |
| Team: | UAB Blazers |
| Sport: | football |
| Conference: | Conference USA |
| Short Conf: | C-USA |
| Division: | West Division |
| Record: | 9–4 |
| Conf Record: | 6–2 |
| Hc Year: | 6th |
| Oc Year: | 5th |
| Def Coach: | David Reeves |
| Dc Year: | 5th |
| Champion: | Independence Bowl champion |
| Bowl Result: | W 31–28 vs. BYU |
The 2021 UAB Blazers football team represented the University of Alabama at Birmingham during the 2021 NCAA Division I FBS football season. The Blazers played their home games at the newly opened Protective Stadium in Birmingham, Alabama, and competed in the West Division of Conference USA (CUSA). The team was coached by sixth-year head coach Bill Clark.
UAB announced its 2021 football schedule on January 27, 2021.[1] The 2021 schedule consisted of 5 home and 6 away games in the regular season, as well as 1 neutral site game.[2] [3]