| Year: | 2021 |
| Team: | Towson Tigers |
| Mode: | football |
| Conference: | Colonial Athletic Association |
| Short Conf: | CAA |
| Record: | 4–7 |
| Conf Record: | 3–5 |
| Head Coach: | Rob Ambrose |
| Hc Year: | 12th |
| Def Coach: | Eric Daniels |
| Dc Year: | 2nd |
| Prev Year: | 2019 |
The 2021 Towson Tigers football team represented Towson University in the 2021 NCAA Division I FCS football season. They were led by 12th-year head coach Rob Ambrose, and played their home games at Johnny Unitas Stadium in Towson, Maryland. They played as members of the Colonial Athletic Association (CAA).