| Year: | 2021 |
| Team: | Toledo Rockets |
| Sport: | football |
| Conference: | Mid-American Conference |
| Division: | West Division |
| Short Conf: | MAC |
| Record: | 7–6 |
| Conf Record: | 5–3 |
| Head Coach: | Jason Candle |
| Hc Year: | 6th |
| Cooff Coach1: | Mike Hallett |
| Cooc1 Year: | 2nd |
| Cooff Coach2: | Robert Weiner |
| Cooc2 Year: | 2nd |
| Def Coach: | Vince Kehres |
| Dc Year: | 2nd |
| Codef Coach1: | Ross Watson |
| Codc1 Year: | 2nd |
| Codef Coach2: | Craig Kuligowski |
| Codc2 Year: | 2nd |
| Stadium: | Glass Bowl |
| Bowl: | Bahamas Bowl |
The 2021 Toledo Rockets football team represented the University of Toledo during the 2021 NCAA Division I FBS football season. The Rockets were led by sixth-year head coach Jason Candle and played their home games at the Glass Bowl in Toledo, Ohio. They competed as members of the West Division of the Mid-American Conference (MAC).
The following Rockets were selected in the 2022 NFL draft following the season.[2]
| 5 | 166 | Tycen Anderson | Defensive back | Cincinnati Bengals | |
| 5 | 172 | Samuel Womack | Defensive back | San Francisco 49ers |