| Year: | 2021 |
| Team: | Tennessee Tech Golden Eagles |
| Sport: | football |
| Conference: | Ohio Valley Conference |
| Short Conf: | OVC |
| Record: | 3–8 |
| Conf Record: | 1–5 |
| Head Coach: | Dewayne Alexander |
| Hc Year: | 4th |
| Off Coach: | Doug Malone |
| Oc Year: | 2nd |
| Off Scheme: | Spread |
| Def Coach: | Donnie Suber |
| Dc Year: | 4th |
| Def Scheme: | 4–2–5 |
| Stadium: | Tucker Stadium |
The 2021 Tennessee Tech Golden Eagles football team represented Tennessee Technological University as a member of the Ohio Valley Conference (OVC) during the 2021 NCAA Division I FCS football season. Led by fourth-year head coach Dewayne Alexander, the Golden Eagles compiled an overall record of 3–8 with a mark of 1–5 in conference play, tying for sixth place in the OVC. Tech Golden played home games at Tucker Stadium in Cookeville, Tennessee.