| Year: | 2021 |
| Team: | St. Thomas Tommies |
| Sport: | football |
| Conference: | Pioneer Football League |
| Short Conf: | PFL |
| Record: | 7–3 |
| Conf Record: | 6–2 |
| Head Coach: | Glenn Caruso |
| Hc Year: | 13th |
| Off Coach: | Bruce Carpenter |
| Oc Year: | 5th |
| Def Coach: | Wallie Kuchinski |
| Dc Year: | 13 |
| Stadium: | O'Shaughnessy Stadium |
| Prev Year: | 2019 |
The 2021 St. Thomas Tommies football team represented the University of St. Thomas in Saint Paul, Minnesota as a member of the Pioneer Football League (PFL) during the 2021 NCAA Division I FCS football season. Led by 13th-year head coach Glenn Caruso, the Tommies compiled an overall record of 7–3 with a mark of 6–2 in conference play, tying for third place in the PFL. St. Thomas played home games at O'Shaughnessy Stadium in Saint Paul, Minnesota.[1]
This was the St. Thomas's first season competing at the NCAA Division I Football Championship Subdivision (FCS) level after transitioning from NCAA Division III. The 2020 season was initially postponed to the spring of 2021 and then canceled because of the COVID-19 pandemic.[2]