| Year: | 2021 |
| Conference: | Southern Conference |
| Division: | I |
| Gender: | Women's |
| Teams: | 8 |
| Arena: | Harrah's Cherokee Center |
| City: | Asheville, North Carolina |
| Champions: | Mercer |
| Titlecount: | 3rd |
| Coach: | Susie Gardner |
| Coachcount: | 3rd |
| Mvp: | Jaron Dougherty |
| Mvpteam: | Mercer |
| Television: | Nexstar, ESPN+ |
The 2021 Southern Conference women's basketball tournament was held March 4–7, 2021, at the Harrah's Cherokee Center in Asheville, North Carolina.
Teams are seeded by record within the conference, with a tiebreaker system to seed teams with identical conference records.
| Seed | School | Conf | Overall | Tiebreaker | |
|---|---|---|---|---|---|
| Samford | 11–2 | 14–8 | ||
| Mercer | 10–3 | 16–6 | ||
| Chattanooga | 9–5 | 14–9 | ||
| Wofford | 7–7 | 11–10 | ||
| UNCG | 6–8 | 8–15 | 2–0 vs. Furman | |
| Furman | 6–8 | 10–13 | 0–2 vs. UNCG | |
| Western Carolina | 3–10 | 6–17 | ||
| ETSU | 1–10 | 3–15 |
All tournament games are streamed on ESPN+. The championship was televised across the region on select Nexstar stations and simulcast on ESPN+.
| Session | Game | Time | Matchup | Television | Attendance | |
|---|---|---|---|---|---|---|
| Quarterfinals – Thursday, March 4 | ||||||
| 1 | 1 | Noon | No. 1 Samford 61 vs. No. 8 ETSU 68 | ESPN+ | ||
| 2 | 2:15 PM | No. 4 Wofford 78 vs. No. 5 UNCG 66 | ||||
| 2 | 3 | 5:00 PM | No. 2 Mercer 76 vs. No. 7 Western Carolina 67 | |||
| 4 | 7:15 PM | No. 3 Chattanooga 40 vs. No. 6 Furman 58 | ||||
| Semifinals – Friday, March 5 | ||||||
| 3 | 5 | Noon | No. 8 ETSU 64 vs. No. 4 Wofford 75 | ESPN+ | ||
| 6 | 2:15 PM | No. 2 Mercer 81 vs. No. 6 Furman 71 | ||||
| Championship Game – Sunday, March 7 | ||||||
| 4 | 7 | Noon | No. 4 Wofford vs. No. 2 Mercer | Nexstar | ||
| Game times in EST. Rankings denote tournament seeding. | ||||||