| Year: | 2021 |
| Conference: | Southern Conference |
| Division: | I |
| Gender: | Men's |
| Teams: | 10 |
| Arena: | Harrah's Cherokee Center |
| City: | Asheville, North Carolina |
| Champions: | UNC Greensboro |
| Titlecount: | 3rd |
| Coach: | Wes Miller |
| Coachcount: | 2nd |
| Mvp: | Isaiah Miller |
| Mvpteam: | UNC Greensboro |
| Television: | ESPN+, ESPNU, ESPN |
The 2021 Southern Conference men's basketball tournament was the postseason men's basketball tournament for the Southern Conference for the 2020–21 season. All tournament games were played at the Harrah's Cherokee Center in Asheville, North Carolina, from March 5 through 8, 2021. The winner of the tournament received the conference's automatic bid to the 2021 NCAA Division I men's basketball tournament.
All ten teams in the Southern Conference were eligible to compete in the conference tournament. Teams were seeded by record within the conference, with a tiebreaker system to seed teams with identical conference records. The top six teams received first-round byes.
| Seed | School | Conference | |
|---|---|---|---|
| 1 | UNC Greensboro | 13–5 | |
| 2 | Wofford | 12–5 | |
| 3 | Furman | 10–5 | |
| 4 | Chattanooga | 9–7 | |
| 5 | ETSU | 8–7 | |
| 6 | VMI | 7–7 | |
| 7 | Mercer | 8–9 | |
| 8 | The Citadel | 5–11 | |
| 9 | Western Carolina | 4–13 | |
| 10 | Samford | 2–9 |
| Game | Time[1] | Matchup | Score | Television | |
|---|---|---|---|---|---|
| First round – Friday, March 5 | |||||
| 1 | 5:30 pm | No. 8 The Citadel vs. No. 9 Western Carolina | 100–86 | ESPN+ | |
| 2 | 8:00 pm | No. 7 Mercer vs No. 10 Samford | 87–59 | ||
| Quarterfinals – Saturday, March 6 | |||||
| 3 | 12:00 pm | No. 1 UNC Greensboro vs. No. 8 The Citadel | 80–72 | ESPN+ | |
| 4 | 2:30 pm | No. 4 Chattanooga vs. No. 5 ETSU | 53–63 | ||
| 5 | 5:30 pm | No. 2 Wofford vs. No. 7 Mercer | 61–62 | ||
| 6 | 8:00 pm | No. 3 Furman vs. No. 6 VMI | 90–91OT | ||
| Semifinals – Sunday, March 7 | |||||
| 7 | 5:00 pm | No. 1 UNC Greensboro vs. No. 5 ETSU | 77–65 | ESPNU | |
| 8 | 7:30 pm | No. 7 Mercer vs. No. 6 VMI | 73–59 | ||
| Final – Monday, March 8 | |||||
| 9 | 7:00 pm | No. 1 UNC Greensboro vs. No. 7 Mercer | 69–61 | ESPN | |
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