| Date: | 10–16 May 2021 |
| Edition: | 5th |
| Surface: | Clay |
| Location: | La Bisbal d'Empordà, Spain |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000+H |
| Champs: |  Irina Khromacheva |
| Champd: | Valentina Ivakhnenko /  Andreea Prisăcariu |
| Before Year: | 2019 |
| Before Name: | Torneig Internacional de Tennis Femení Solgironès |
| After Name: | Torneig Internacional de Tennis Femení Solgironès |
The 2021 Solgironès Open Catalunya was a professional women's tennis tournament played on outdoor clay courts. It was the fifth edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in La Bisbal d'Empordà, Spain between 10 and 16 May 2021.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Arantxa Rus | 85 | 1 | ||
| Kaja Juvan | 99 | 2 | ||
 Slovakia | Viktória Kužmová | 106 | 3 | |
 Hungary | Tímea Babos | 107 | 4 | |
| Anna-Lena Friedsam | 111 | 5 | ||
| Stefanie Vögele | 127 | 6 | ||
 Belgium | Greet Minnen | 129 | 7 | |
| Belgium | Ysaline Bonaventure | 130 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry using a protected ranking:
The following players received entry from the qualifying draw:
Marina Bassols Ribera
Cristiana Ferrando Guiomar Maristany Jessica Pieri Andreea Prisăcariu Olga Sáez LarraSee main article: 2021 Solgironès Open Catalunya – Singles.
Irina Khromacheva def. Arantxa Rus, 6–4, 1–6, 7–6(10–8)See main article: 2021 Solgironès Open Catalunya – Doubles.
Valentina Ivakhnenko / Andreea Prisăcariu def. Mona Barthel / 
Mandy Minella, 6–3, 6–1
