| Competition: | Prince Takamado JFA U-18 Premier League |
| Season: | 2021 |
| Dates: | 3 April – 12 December |
| Winners: | Aomori Yamada (3rd title) Sanfrecce Hiroshima (5th title) |
| Relegated: | East: Urawa Red Diamonds West: Kyoto Sanga |
| League Topscorer: | East: Kanta Chiba (18 goals) West: Isa Sakamoto (15 goals) |
| Biggest Home Win: | |
| Biggest Away Win: | |
| Highest Scoring: | |
| Matches: | 165 |
| Total Goals: | 530 |
| Prevseason: | 2019 |
| Nextseason: | 2022 |
The was the 32nd season of the main competition for under-18 teams in Japan, the 11st after rebranding the competition to the current "Premier League" format, and the last season with 20 clubs participating in the league. It returned after a one-year absence, since the 2020 tournament was cancelled due to COVID-19.
Aomori Yamada High School won the Premier League East, and Sanfrecce Hiroshima won the Premier League West. By default, both group winners would make the final, but it ended up cancelled due to COVID-19 precautions.[1]
| Team | Prefecture |
|---|---|
| Aomori Yamada High School | Aomori |
| Omiya Ardija | Saitama |
| Urawa Red Diamonds | Saitama |
| Ichiritsu Funabashi High School | Chiba |
| Kashiwa Reysol | Chiba |
| Ryutsu Keizai University Kashiwa High School | Chiba |
| Tokyo | |
| Kanagawa | |
| Kanagawa | |
| Shimizu S-Pulse | Shizuoka |
| Team | Prefecture |
|---|---|
| Júbilo Iwata | Shizuoka |
| Nagoya Grampus | Aichi |
| Kyoto Sanga | Kyoto |
| Gamba Osaka | Osaka |
| Cerezo Osaka | Osaka |
| Vissel Kobe | Hyogo |
| Sanfrecce Hiroshima | Hiroshima |
| Higashi Fukuoka High School | Fukuoka |
| Saga | |
| Ohzu High School | Kumamoto |
The teams were ranked by their points-per-game ratio, as many matches could not be played due to issues related to COVID-19.[2]
Only for this edition, there were six direct promotions from the Prince Leagues while only two teams got relegated, to accommodate the transition from 20 to 24 teams, that started in the following season.[3]
Qualified to the stage were the 18 (instead of the usual 16) top-ranked teams of the nine Prince League divisions. They were divided into six blocks, with their respective block winners, highlighted in bold qualifying for next season's Premier League.
| Rank | Player | Club | Goals[4] |
|---|---|---|---|
| 1 |  Kanta Chiba | Shimizu S-Pulse | 18 |
| 2 | Kotaro Uchino | Yokohama F. Marinos | 13 |
| 3 | Sera Watanabe | Aomori Yamada | 9 |
| Ota Yamamoto | Kashiwa Reysol | ||
| 5 | Kuryu Matsuki | Aomori Yamada | 8 |
| Leon Nozawa | FC Tokyo | ||
| Taishin Yamazaki | Yokohama FC | ||
| 8 | Sota Fujimori | Aomori Yamada | 6 |
| Riku Gunji | Ichiritsu Funabashi | ||
| Seita Kaneko | Shimizu S-Pulse | ||
| Hidetaka Maie | Kashiwa Reysol | ||
| Yugo Masukake | Kashiwa Reysol | ||
| Masaki Nasukawa | Aomori Yamada | ||
| Rin Yamazaki | Omiya Ardija | ||
| Rank | Player | Club | Goals[5] |
|---|---|---|---|
| 1 | Isa Sakamoto | Gamba Osaka | 15 |
| 2 | Hayato Manabe | Nagoya Grampus | 12 |
| 3 | Ryo Tanada | Sanfrecce Hiroshima | 10 |
| 4 | Harumi Minamino | Gamba Osaka | 9 |
| Eijiro Takayanagi | Sanfrecce Hiroshima | ||
| 6 | Naoki Asano | Gamba Osaka | 7 |
| Sota Kitano | Cerezo Osaka | ||
| 8 | Toshiki Ando | Sagan Tosu | 5 |
| Shinnosuke Katsushima | Kyoto Sanga | ||
| Daichi Morita | Ohzu | ||