See main article: 2021 Open Quimper Bretagne.
Andrey Golubev and Aleksandr Nedovyesov were the defending champions[1] but chose not to defend their title.
Grégoire Barrère and Albano Olivetti won the title after defeating James Cerretani and Marc-Andrea Hüsler 5–7, 7–6(9–7), [10–8] in the final.