| Champ: | Polona Hercog |
| Runner: |  Clara Burel |
| Score: | Walkover |
| Edition: | 1st |
| Type: | singles doubles |
See main article: article and 2021 Oeiras Ladies Open.
This was the first edition of the tournament.[1]
Polona Hercog won the title after Clara Burel withdrew before the final.
All seeds receive a bye into the second round.