See main article: article and 2021 Mercer Tennis Classic.
Katarzyna Kawa and Magdalena Fręch were the defending champions[1] but Fręch chose not to participate. Kawa partnered alongside Tereza Mihalíková, but they lost in the first round to Emily Appleton and Fernanda Contreras.
Quinn Gleason and Catherine Harrison won the title, defeating Alycia Parks and Alana Smith in the final, 6–2, 6–2.