See main article: article and 2021 WTA Lyon Open.
Laura Ioana Paar and Julia Wachaczyk were the defending champions[1] but lost in the quarterfinals to Viktória Kužmová and Arantxa Rus.
Kužmová and Rus went on to win the title, defeating Eugenie Bouchard and Olga Danilović in the final, 3–6, 7–5, [10–7].