| Competition: | Liga de Elite |
| Season: | 2021 |
| Dates: | 12 March – 14 November |
| Winners: | Chao Pak Kei (2nd title) |
| Relegated: | Hang Sai |
| Continentalcup1: | AFC Cup |
| Continentalcup1 Qualifiers: | Chao Pak Kei |
| Matches: | 90 |
| Total Goals: | 399 |
| League Topscorer: | Carlos Leonel (35 goals) |
| Prevseason: | 2020 |
| Nextseason: | 2022 |
The 2021 Liga de Elite was the 49th season of the Liga de Elite, the top Macanese league for association football clubs since its establishment in 1973. The season began on 12 March 2021 and ended on 14 November 2021.[1]