| Liga 3 South Kalimantan | |
| Year: | 2021 |
| Dates: | 1 November 2021[1] |
| Num Teams: | 14 |
| Defending Champions: | Persetala Tanah Laut |
| Champions: | Persemar Martapura |
| Runner-Up: | Batulicin Putra 69 |
| Prevseason: | 2019 |
| Nextseason: | 2022 |
The 2021 Liga 3 South Kalimantan was the sixth season of Liga 3 South Kalimantan as a qualifying round for the national round of the 2021–22 Liga 3.
Persetala Tanah Laut were the defending champion.
There are 14 teams participated in the league this season, divided into 2 groups of seven.
| Team | Location | |
|---|---|---|
| Barabai | Central Hulu Sungai | |
| Batulicin Putra 69 | Tanah Bumbu | |
| Kotabaru | Kotabaru | |
| Perseam Amuntai | North Hulu Sungai | |
| Persebaru Banjarbaru | Banjarbaru | |
| Persehan Marabahan | Barito Kuala | |
| Persemar Martapura | Banjar Regency | |
| Persepan Pagatan | Tanah Bumbu | |
| Perseran Rantau | Tapin | |
| Persetala Tanah Laut | Tanah Laut | |
| Persitam Tamban | Barito Kuala | |
| Peseban Banjarmasin | Banjarmasin | |
| PS Kab. Tapin | Tapin | |
| Talenta Banua | Banjar Regency |