| Liga 3 Papua | |
| Year: | 2021 |
| Dates: | 26 November–20 December 2021 |
| Num Teams: | 9 |
| Defending Champions: | Persemi Mimika |
| Champions: | Toli[1] |
| Count: | 1 |
| Runner-Up: | Persigubin Pegunungan Bintang |
| Third: | Persimer Merauke |
| Fourth: | Dogiyai |
| Prevseason: | 2019 |
| Nextseason: | 2022 |
The 2021 Liga 3 Papua was the fourth season of Liga 3 Papua as a qualifying round for the national round of the 2021–22 Liga 3.
Persemi Mimika were the defending champion.
There was 9 teams participated in the league this season.[2]
| Team | Location | |
|---|---|---|
| Dogiyai | Dogiyai | |
| Mamberamo United | Great Mamberamo | |
| Persemi Mimika | Mimika | |
| Persigubin Pegunungan Bintang | Bintang Mountain Regency | |
| Persiker Keerom | Keerom | |
| Persimer Merauke | Merauke | |
| Persimi Sarmi | Sarmi | |
| PS Elang Brimob | Jayapura | |
| Toli | Tolikara |