| Year: | 2021 |
| Team: | Lafayette Leopards |
| Sport: | football |
| Conference: | Patriot League |
| Short Conf: | Patriot |
| Record: | 3–8 |
| Conf Record: | 2–4 |
| Head Coach: | John Garrett |
| Hc Year: | 5th |
| Def Coach: | Doug McFadden |
| Dc Year: | 2nd |
The 2021 Lafayette Leopards football team represented Lafayette College in the 2021 NCAA Division I FCS football season. The Leopards, led by fifth-year head coach John Garrett, played their home games at Fisher Stadium as a member of the Patriot League.
See also: 2021 Air Force Falcons football team.
| style= | Pregame line! | style= | Over/under |
|---|---|---|---|
| AF –40.5 | 49.5[2] |
| Statistics | Lafayette | Air Force |
|---|---|---|
| First downs | 12 | 24 |
| Total yards | 287 | 420 |
| Rushing yards | 43 | 370 |
| Passing yards | 244 | 50 |
| Turnovers | 2 | 0 |
| Time of possession | 25:39 | 34:21 |
| Team | Category | Player | Statistics |
|---|---|---|---|
| Lafayette | Passing | Aaron Angelos | 10/16, 158 yards |
| Rushing | Jaden Sutton | 7 carries, 38 yards | |
| Receiving | Julius Young | 8 receptions, 147 yards, 1 TD | |
| Air Force | Passing | Haaziq Daniels | 3/5, 50 yards |
| Rushing | 25 carries, 111 yards | ||
| Receiving | 2 receptions, 27 yards |