| Date: | 25–31 October 2021 |
| Edition: | 27th |
| Surface: | Hard / Indoor |
| Location: | Poitiers, France |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $80,000 |
| Champs: |  Chloé Paquet |
| Champd: |  Mariam Bolkvadze /  Samantha Murray Sharan |
| Before Year: | 2019 |
The 2021 Internationaux Féminins de la Vienne was a professional women's tennis tournament played on indoor hard courts. It was the twenty-seventh edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Poitiers, France between 25 and 31 October 2021.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| France | Océane Dodin | 92 | 1 | |
| France | Harmony Tan | 109 | 2 | |
 Hungary | Tímea Babos | 149 | 3 | |
| France | Chloé Paquet | 165 | 4 | |
| France | Amandine Hesse | 175 | 5 | |
| Georgia | Mariam Bolkvadze | 183 | 6 | |
 Ukraine | Daria Snigur | 184 | 7 | |
 Austria | Julia Grabher | 191 | 8 |
The following players received wildcards into the singles main draw:
Estelle Cascino Émeline Dartron Léolia Jeanjean Karen MarthiensThe following players received entry from the qualifying draw:
Audrey Albié Alicia Barnett Sarah Beth Grey Amandine Monnot Victoria Muntean Mallaurie Noël Alice Robbe
Karman ThandiSee main article: 2021 Internationaux Féminins de la Vienne – Singles.
Chloé Paquet def. Simona Waltert, 6–4, 6–3See main article: 2021 Internationaux Féminins de la Vienne – Doubles.
Mariam Bolkvadze / Samantha Murray Sharan def. Audrey Albié / Léolia Jeanjean, 7–6(7–5), 6–0