| Date: | 16–22 August 2021 |
| Edition: | 1st |
| Surface: | Clay |
| Location: | San Bartolomé de Tirajana, Spain |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: | Arantxa Rus |
| Champd: | Arianne Hartono /  Olivia Tjandramulia |
The 2021 ITF World Tennis Tour Maspalomas was a professional women's tennis tournament played on outdoor clay courts. It was the first edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in San Bartolomé de Tirajana, Spain between 16 and 22 August 2021.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Arantxa Rus | 80 | 1 | ||
 Serbia | Aleksandra Krunić | 197 | 2 | |
 Austria | Julia Grabher | 204 | 3 | |
 Japan | Yuki Naito | 221 | 4 | |
| Australia | Seone Mendez | 224 | 5 | |
 France | Diane Parry | 245 | 6 | |
 Italy | Lucrezia Stefanini | 251 | 7 | |
 Mexico | Ana Sofía Sánchez | 256 | 8 |
The following players received wildcards into the singles main draw:
Jéssica Bouzas Maneiro Ana Lantigua de la Nuez Guiomar Maristany Carlota Martínez CírezThe following player received entry using a protected ranking:
The following player received entry as a special exempt:
The following players received entry from the qualifying draw:
Jessie Aney
Ilona Georgiana Ghioroaie
Victoria Jiménez Kasintseva Ashley Lahey Estela Pérez Somarriba
Maria TimofeevaSee main article: 2021 ITF World Tennis Tour Maspalomas – Singles.
Victoria Jiménez Kasintseva, 6–0, 6–1See main article: 2021 ITF World Tennis Tour Maspalomas – Doubles.
Olivia Tjandramulia def. 
María Lourdes Carlé / Julieta Estable, 6–4, 2–6, [10–7]