| Date: | 9–15 August 2021 |
| Edition: | 1st |
| Surface: | Clay |
| Location: | San Bartolomé de Tirajana, Spain |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $60,000 |
| Champs: | Arantxa Rus |
| Champd: |  Elina Avanesyan / Oksana Selekhmeteva |
The 2021 ITF World Tennis Tour Gran Canaria was a professional women's tennis tournament played on outdoor clay courts. It was the first edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in San Bartolomé de Tirajana, Spain between 9 and 15 August 2021.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Arantxa Rus | 79 | 1 | ||
 Egypt | Mayar Sherif | 119 | 2 | |
 Romania | Jaqueline Cristian | 149 | 3 | |
 France | Tessah Andrianjafitrimo | 201 | 4 | |
 Austria | Julia Grabher | 205 | 5 | |
| Despina Papamichail | 224 | 6 | ||
| Daniela Seguel | 226 | 7 | ||
 Spain | Rebeka Masarova | 231 | 8 |
The following players received wildcards into the singles main draw:
Lucía Cortez Llorca Jaqueline Cristian Ana Lantigua de la Nuez Leyre Romero GormazThe following player received entry using a junior exempt:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
See main article: 2021 ITF World Tennis Tour Gran Canaria – Singles.
Mayar Sherif, 6–4, 6–2See main article: 2021 ITF World Tennis Tour Gran Canaria – Doubles.
Elina Avanesyan / Oksana Selekhmeteva def. Arianne Hartono / 
Olivia Tjandramulia, 7–5, 6–2
