| Champ: |  Julia Grabher |
| Runner: |  Lucia Bronzetti |
| Score: | 6–2, 6–3 |
| Edition: | 1st |
| Type: | singles doubles |
| After Name: | Bellinzona Ladies Open – Singles |
See main article: article and 2021 ITF Women's World Tennis Tour – Bellinzona.
This was the first edition of the tournament.
Julia Grabher won the title, defeating Lucia Bronzetti in the final, 6–2, 6–3.
All seeds receive a bye into the second round.