| Date: | 27 September–3 October 2021 |
| Edition: | 1st |
| Surface: | Hard |
| Location: | Le Neubourg, France |
| Category: | ITF Women's World Tennis Tour |
| Prize Money: | $80,000+H |
| Champs: |  Mihaela Buzărnescu |
| Champd: |  Robin Anderson /  Amandine Hesse |
The 2021 ITF Féminin Le Neubourg was a professional women's tennis tournament played on outdoor hard courts. It was the first edition of the tournament which was part of the 2021 ITF Women's World Tennis Tour. It took place in Le Neubourg, France between 27 September and 3 October 2021.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Montenegro | Danka Kovinić | 80 | 1 | |
| France | Harmony Tan | 120 | 2 | |
| Romania | Mihaela Buzărnescu | 175 | 3 | |
 Hungary | Anna Bondár | 179 | 4 | |
| France | Amandine Hesse | 180 | 5 | |
 Italy | Lucrezia Stefanini | 199 | 6 | |
| France | Jessika Ponchet | 207 | 7 | |
| Indy de Vroome | 212 | 8 |
The following players received wildcards into the singles main draw:
Manon Arcangioli Loïs Boisson Salma Djoubri Lucie Nguyen TanThe following player received entry using a protected ranking:
The following player received entry as a junior exempt:
The following players received entry from the qualifying draw:
Audrey Albié Estelle Cascino
Sarah Beth Grey
Momoko Kobori
Anna Kubareva
Laura Pigossi Aravane Rezaï Iryna ShymanovichThe following player received entry as a lucky loser:
See main article: 2021 ITF Féminin Le Neubourg – Singles.
Mihaela Buzărnescu def. Anna Bondár, 6–1, 6–3See main article: 2021 ITF Féminin Le Neubourg – Doubles.
Robin Anderson / Amandine Hesse def. Estelle Cascino / Sarah Beth Grey, 6–3, 7–6(7–2)
