| Score: | 6–2, 7–6(7–3) |
| Type: | singles doubles |
| Before Year: | 2019 |
See main article: article and 2021 Hall of Fame Open.
Marcel Granollers and Sergiy Stakhovsky were the reigning champions from when the tournament was last held in 2019, but chose not to defend their title.[1]
William Blumberg and Jack Sock won the title, defeating Austin Krajicek and Vasek Pospisil in the final, 6–2, 7–6(7–3).[2]