See main article: article and 2021 Grand Est Open 88.
Georgina García Pérez and Oksana Kalashnikova were the defending champions[1] but chose not to participate.
Anna Danilina and Ulrikke Eikeri won the title, defeating Dalma Gálfi and Kimberley Zimmermann in the final, 6–0, 1–6, [10–4].