| Year: | 2021 |
| Team: | Furman Paladins |
| Sport: | football |
| Conference: | Southern Conference |
| Short Conf: | SoCon |
| Record: | 6–5 |
| Conf Record: | 4–4 |
| Head Coach: | Clay Hendrix |
| Hc Year: | 5th |
| Off Coach: | George Quarles |
| Oc Year: | 4th |
| Def Coach: | Duane Vaughn |
| Dc Year: | 3rd |
| Captain: | Hamp Sisson, Devin Wynn, Elijah McKoy, DiMarcus Clay |
| Stadium: | Paladin Stadium |
The 2021 Furman Paladins team represented Furman University as a member of the Southern Conference (SoCon) during the 2021 NCAA Division I FCS football season. Led by fifth-year head coach Clay Hendrix, the Paladins compiled an overall record of 6–5 with a mark of 4–4 in conference play, placing in a three-way tie for fourth in the SoCon. Furman played home games at Paladin Stadium in Greenville, South Carolina.