See main article: 2021 Challenger de Santiago II.
Sebastián Báez was the defending champion[1] but lost in the final to Juan Pablo Varillas.
Varillas won the title after defeating Báez 6–4, 7–5 in the final.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "2021 Challenger de Santiago II – Singles".
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