See main article: 2021 Challenger Eckental.
Dustin Brown and Antoine Hoang were the defending champions[1] but only Brown chose to defend his title, partnering Andrea Vavassori. Brown lost in the quarterfinals to Ruben Bemelmans and Daniel Masur.
Roman Jebavý and Jonny O'Mara won the title after defeating Bemelmans and Masur 6–4, 7–5 in the final.