| Year: | 2021 |
| Team: | Central Connecticut Blue Devils |
| Sport: | football |
| Conference: | Northeast Conference |
| Short Conf: | NEC |
| Record: | 4–7 |
| Conf Record: | 4–3 |
| Head Coach: | Ryan McCarthy |
| Hc Year: | 3rd |
| Off Coach: | Jeff Ambrosie |
| Oc Year: | 3rd |
| Def Coach: | Ron DiGravio |
| Dc Year: | 3rd |
| Stadium: | Arute Field |
| Prev Year: | 2019 |
The 2021 Central Connecticut Blue Devils football team represented Central Connecticut State University as a member of the Northeast Conference (NEC) during the 2021 NCAA Division I FCS football season. The Blue Devils, led by third-year head coach Ryan McCarthy, played their home games at Arute Field. Central Connecticut compiled an overall record of 4–7 with a mark of 4–3 in conference play, tying for fourth place in the NEC.