| Champ: |  Sebastián Báez |
| Runner: |  Thiago Monteiro |
| Score: | 6–1, 6–4 |
| Type: | singles doubles |
See main article: 2021 Campeonato Internacional de Tênis de Campinas.
Francisco Cerúndolo was the defending champion[1] but lost in the semifinals to Sebastián Báez.
Báez won the title after defeating Thiago Monteiro 6–1, 6–4 in the final.