| Season: | 2021 |
| Competition: | Cambodian Second League |
| Winners: | Bati Academy |
| Biggest Home Win: | |
| Biggest Away Win: | |
| Highest Scoring: | |
| Matches: | 28 |
| Total Goals: | 88 |
| Longest Wins: | |
| Longest Unbeaten: | |
| Longest Losses: | |
| Prevseason: | 2020 |
| Nextseason: | 2022 |
The 2021 Cambodian Second League will be the fourth season of Cambodian Second League, the second-tier of Cambodian football. It was first started off in 2016 by the Football Federation of Cambodia.A total of eight teams will play each other a single round robin matches. The winner will promote to 2022 Cambodian League.However, due to the new policies and regulations implemented by the newly established Cambodian League Company; none of the teams from the 2021 Second League season would be promoted to the first division because they had failed to meet the licensing requirements.[1]
| Team | Location | Stadium |
|---|---|---|
| ISI Dangkor Senchey | Phnom Penh | KMH Stadium |
| Koh Kong | Koh Kong Province | Koh Kong Stadium |
| Tiffy Army U-21 | Phnom Penh | RCAF Old Stadium |
| Bati Academy | Takeo | Bati Football School |
| Rithi Sen | Kampong Chhnang Province | Kampong Chhnang Stadium |
| Siem Reap | Siem Reap Province | Siem Reap Stadium |
| Banteay Mean Chey | Banteay Mean Chey Province | Kla Kon Stadium |
| Tbong Khmum | Tbong Khmum Province | Tbong Khmum Stadium |
As of 11 December 2021.
| Rank | Player | Club | Goals |
|---|---|---|---|
| 1 | San Bora | Koh Kong | 5 |
| 2 | Chan Vibol David | Bati Academy | 4 |
| 3 | Khorn Soben | Bati Academy | 3 |
| Konay Ansari | ISI Dangkor Senchey | 3 | |
| Rath Virak | ISI Dangkor Senchey | 3 | |
| Sari Taymo | Tbong Khmum | 3 | |
| 7 | 8 Players | 5 teams | 2 |
| 15 | 13 Players | 6 teams | 1 |
As of 11 December 2021.
| Rank | Player | Club | Cleansheets |
|---|---|---|---|
| 1 | Reth Lyheng | Bati Academy | 3 |
| 2 | Chheng Chantha | ISI Dangkor Senchey | 2 |
| 3 | Khandeth Sothea Vathana | Koh Kong | 1 |
| Samath Ravy | Tbong Khmum | 1 | |
| Awards | Nation/Name | Club | |
|---|---|---|---|
| Player of the season | Meuet Setsen | Tbong Khmum | |
| Goalkeeper of the season | Reth Lyheng | Bati Academy | |
| Coach of the season |  Koji Gyotoku | Bati Academy |