| Year: | 2021 |
| Team: | Bucknell Bison |
| Sport: | football |
| Conference: | Patriot League |
| Short Conf: | Patriot |
| Record: | 1–10 |
| Conf Record: | 0–6 |
| Head Coach: | Dave Cecchini |
| Hc Year: | 3rd |
| Off Coach: | Jason Miran |
| Oc Year: | 3rd |
| Def Coach: | Isaac Collins |
| Dc Year: | 1st |
The 2021 Bucknell Bison football team represented Bucknell University in the 2021 NCAA Division I FCS football season. The Bison, led by third-year head coach Dave Cecchini, played their home games at Christy Mathewson–Memorial Stadium as a member of the Patriot League.