See main article: article and 2021 Boar's Head Resort Women's Open.
Asia Muhammad and Taylor Townsend were the defending champions, having won the last edition in 2019,[1] however both players chose not to participate.
Anna Danilina and Arina Rodionova won the title, defeating Erin Routliffe and Aldila Sutjiadi in the final, 6–1, 6–3.